Grand Opening of New University of Massachusetts Lowell State-of-the-art, Pilot-scale Lyophilization Facility

[28 October 2019]

SP Scientific was delighted to support today the ribbon-cutting event officially launching the new UMass Lowell state-of-the-art, pilot-scale lyophilization facility. As the newest member of UMass Lowell’s Core Research Facilities, this non-GMP Lyophilization Lab (LyoBay) provides an R&D test bed for process development, scale-up and the development and application of new process analytical technologies. It will also serve as a user facility for pre-clinical process development and training to support the local and national biotechnology industry. 

This facility includes a new SP Scientific S20 LyoConstellation production freeze dryer. LyoConstellation is a Line of Sight-enabled freeze-drying system with very powerful refrigeration, delivering an expanded equipment capability and a large process space. This allows the development of highly aggressive cycles and the mapping of the furthest reaches of theoretical design space for a formulation. When handling high-value active pharmaceutical ingredient (API), and with a need to bring product to market as quickly and safely as possible, LyoConstellation addresses early stage development under aseptic and controlled conditions. This means product behaves in the same manner once it is ready for scale-up and eventually ready for commercialization.

This new pilot-scale lyophilization facility, an important addition to the UMass Lowell innovation ecosystem, was developed with generous support from the Massachusetts Life Sciences Center and from the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL). A NIIMBL funded project team led by Physical Sciences Inc. (PSI) of Andover, MA, and including UMass Lowell, the University of Connecticut, Purdue University, Merck, and Genentech, are guiding the facility development and will be the inaugural users of the facility developing process scale-up tools to support improved biopharmaceutical manufacturing. 

As well as the grand ribbon-cutting opening, the celebration included a list of invited guest speakers including representatives from PSI Inc., Pfizer, NIIMBL, Mass Life Sciences Center, UMass Lowell, as well as local and state government officials. The event included a tour of the new facility and an opportunity to visit some of the other R&D labs available in UMass Lowell’s Core Research Facilities.

For general information about the UMass Lowell Core Research Facilities, please visit

For further information on the LyoConstellation S20 system please visit or contact SP Scientific on Toll Free (800) 523-2327 (+44-1473-240000 in Europe). 

About SP Scientific

SP Scientific is a leading manufacturer of freeze dryers / lyophilizers, aseptic vial washing and tray loading machines, temperature control/thermal management, centrifugal evaporators and concentrators, glassware washers, and controlled environmental rooms and chambers. The company sells its products under well-known brands including VirTis, Hull, PennTech, FTS Systems, Genevac and Hotpack. SP Scientific has ISO 9001:2015 registered production facilities in the USA and Europe.


UMass Lowell unveiled its new Lyophilization Bay on Monday, Oct 28 at the Mark and Elisia Saab Emerging Technologies and Innovation Center. Shown at the event were, from left, UMass Lowell Chemical Engineering Prof. Seongkyu Yoon; Physical Sciences Inc. Principal Research Scientist William Kessler; UMass Lowell Core Research Facilities Executive Director Karen Hamlin; UMass Lowell Vice Chancellor for Research and Economic Development Julie Chen; John Erickson, senior fellow, National Institute for Innovation in Manufacturing Biopharmaceuticals; UMass Lowell Chancellor Jacquie Moloney; Massachusetts Life Sciences Center (MLSC) President and CEO Travis McCready; CuriRx President and CEO Indu Javeri; Physical Sciences Inc. President and CEO David Green; Pfizer Vice President of Pharmaceutical Research and Development Nicholas Warne; and MLSC Director of Industry Programs Carla Reimhold.

(Photo credit: Tory Wesnofske for UMass Lowell).

Further Info / Illustrative Image:      

Marketing: Chris Levoi - tel. +44-7776-589551 & email